| abstract |
PROBLEM TO BE SOLVED: To provide a PPARγ activator containing the substance as an active ingredient for the purpose of finding a substance having agonist activity for PPARγ. Another object of the present invention is to provide an agent for preventing and / or improving lifestyle-related diseases such as insulin resistance, hyperlipidemia, diabetes, obesity and Alzheimer's disease containing the substance. [MEANS FOR SOLVING PROBLEMS] As a result of diligent searches for PPARγ agonists from various plant extracts, it has been found that monoacylglycerol (monoglyceride) has not only PPARα agonist activity but also high PPARγ agonist activity. Furthermore, hyperlipidemia, diabetes, obesity And it discovered having the effect which prevents and improves Alzheimer's disease. [Selection figure] None |