| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9019c0ce5cb7b82c85e121f6cac86dce
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d75d1a4caed60a9316608ed9c231546c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c54ea7ce4fd2b26723710f44e9f30698
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_600a0547c1117dfc8e35d57f20d02ee9 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-18 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 |
| filingDate |
2006-10-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7af7a852b3b4b584a16fde9c7f5b0ed5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d1f5baf60bdcda2b926e3e9c3bf09255
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9db723d73389db61e7532e00a29aa760 |
| publicationDate |
2008-05-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-2008099602-A |
| titleOfInvention |
Control method of distribution of mutation sites in variable region of antibody gene |
| abstract |
PROBLEM TO BE SOLVED: To provide a method for introducing a mutation into the entire region of an antibody gene variable region. [MEANS FOR SOLVING PROBLEMS] The present invention selectively reduces or loses the function of histone deacetylase (hereinafter referred to as HDAC) 2 gene, or selectively reduces or loses the activity or function of HDAC2 protein. The present invention provides a method for introducing various mutations into an antibody gene region present on the chromosome of an immune cell. [Selection] Figure 4 |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2020099341-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106414717-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-WO2015167011-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015167011-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112877292-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-7236741-B2 |
| priorityDate |
2006-10-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |