http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2008069181-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d45f2cc0a7f8047b68d7e339f61ff56e |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D473-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D473-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-003 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D473-34 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D473-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D473-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D473-18 |
| filingDate | 2007-12-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_879583a5b33908b470425618e8c057d9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_63875f7295579cff2e46afa0e450e473 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0e85bb3d93fe6cb1d574edd5d7c67ed2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6750c4f6792bafaaf8e58ef073cbbe40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_df3112342d02202291744ab5fab62324 |
| publicationDate | 2008-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2008069181-A |
| titleOfInvention | Improved synthons for synthesis and methods for deprotection of peptide nucleic acids under mild conditions |
| abstract | Provided is a method for synthesizing a new PNA synthon that overcomes the problems of the prior art. A method for synthesizing a carbamate-protected nucleobase side chain moiety comprising steps (a) to (e): (a) a partially protected group having an exocyclic amino group and a heterocyclic N-atom. (B) reacting the exocyclic amino group of this partially protected nucleobase compound with a carbonyl equivalent having electron affinity to synthesize an N-substituted intermediate compound (c) Reacting the compound with an alcohol to synthesize a fully protected nucleobase compound having a carbamate protected amino group (d) reacting the fully protected nucleobase compound with a metal alkoxide or metal hydroxide to provide carbamate protection The metal salt of the nucleoside side chain was synthesized, and this metal salt has a main chain carboxylic acid group. (E) The acid was used under conditions suitable for proton addition of the main chain carboxylic acid group or heterocyclic N-atom. Carbamate protected Obtaining a nucleobase side chain moiety. [Selection figure] None |
| priorityDate | 1995-06-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
| Predicate | Subject |
|---|---|
| isDiscussedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID457814461 http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID419538410 http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID702 |
Total number of triples: 28.