| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_faf522b8b83eded745c73018576219ba |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-60
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-10 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4702 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-15 |
| filingDate |
2006-09-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1d312e94d6edcc6282dea7a4bd4d51ff
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f27a7925c1512e2e089fa33a5625d9b6 |
| publicationDate |
2008-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-2008067655-A |
| titleOfInvention |
Drug screening method for controlling in vivo hypoxic response device |
| abstract |
The present invention provides a screening method for compounds capable of controlling the stability of HIF-1α. The stability of HIF-1α is improved by bringing a test substance into contact with a cell expressing a HIF-1α protein fragment and a fusion protein containing HaloTag protein, and detecting fluorescence of the HaloTag protein in the cell. Compounds that can be controlled can be screened. [Selection figure] None |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2013236938-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019098246-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11697679-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-7303551-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-WO2019098246-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2010085108-A |
| priorityDate |
2006-09-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |