| abstract |
The present invention provides compounds of formula (I) and further provides methods for synthesizing them and methods for using them in the treatment of cancer: Here, R 1 to R 7 , X 1 , X 2 , R, Q, and n are as defined in the present specification. Recognizing the need for accessing and exploring new derivatives of hemiasterlin and the biological activity of this type of peptide in general, the present invention provides novel peptide compounds that exhibit anti-cancer activity. Therefore, the compounds of the present invention, and their pharmaceutical compositions, are useful for treating cancer. |