| Predicate |
Object |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10T436-143333
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-70
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-7233
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2030-027 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H17-08 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-70 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-88
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-86
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-74
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-26
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-72
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-64 |
| filingDate |
2005-05-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate |
2007-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-2007536526-A |
| titleOfInvention |
Methods and systems for detecting, identifying and quantifying macrolides and their impurities |
| abstract |
The present invention relates to reverse phase high performance liquid chromatography (RP-HPLC) methods and systems for detecting macrolides and for detecting, identifying and quantifying impurities in samples containing macrolides. The present invention provides a method for detecting macrolide in a test sample in which the major component by weight of the test sample is macrolide, the method comprising: a) reverse phase high performance liquid chromatography (a) RP-HPLC) applying to the column; b) eluting the test sample with a gradient mobile phase containing volatile buffer, water, acetonitrile and alcohol; and c) electrochemically treating the effluent from the column. Monitoring with a static detector or a mass spectrometric detector to detect a peak current or mass peak corresponding to the macrolide, respectively. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2009222421-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11333639-B2 |
| priorityDate |
2004-05-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |