abstract |
The present invention is useful as a p38 MAP kinase inhibitor, having the formula [I] (In the formula, R 1 represents halogen, nitro, alkyl or the like. R 2 represents hydrogen, alkyl or the like. Ring A represents 2-oxo-4-imidazoline-3,4-diyl and the like. Ring B represents cycloalkyl or a monocyclic saturated heterocyclic group. X represents CH and N. Y represents a single bond, CO, or SO 2 . Z represents O, NH or the like. Ring C represents an aryl or heterocyclic group. ) Or a pharmaceutically acceptable salt thereof. |