http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2007535466-A
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-29 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-635 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-18 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-635 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P5-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-29 |
filingDate | 2003-01-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2007-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-2007535466-A |
titleOfInvention | Conformationally restricted parathyroid hormone (PTH) analogs with lactam bridges |
abstract | The present invention relates to methods of treatment of conformationally restricted parathyroid hormone (PTH) analogs and derivatives of these analogs in a mammalian condition characterized by bone mass loss. These analogs and derivatives include PTH polypeptide derivatives containing at least one Glu or Lys substitution at the 6 and / or 10 positions, some with a lactam bridge between the side chains introduced into Lys and Glu. Yes. The present invention relates to peptides PTH (1-34), PTH (1-33), PTH (1-32), PTH (1-31), PTH (1-30), PTH (1-29), PTH (1 -28), PTH (1-27), PTH (1-26), PTH (1-25), PTH (1-24), PTH (1-23), PTH (1-22), PTH (1- 21), PTH (1-20), PTH (1-19), PTH (1-18), PTH (1-17), PTH (1-16), PTH (1-15), PTH (1-14 ), PTH (1-13), PTH (1-12), PTH (1-11), PTH (1-10), PTH (1-9) derivatives. The present invention also provides a method for preparing PTH analogs. Furthermore, the present invention is characterized by the need for undesirable bone loss or bone growth in order to elevate cAMP in cells, for example, when treating fractures or cartilage disorders and as deemed necessary. Relates to treating a condition. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011062073-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2020040998-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019059303-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2021167354-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-WO2019059303-A1 |
priorityDate | 2003-01-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 241.