| Predicate |
Object |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-70582
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-93
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-82
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7088
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-82
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-705
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04 |
| filingDate |
2005-04-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate |
2007-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-2007535315-A |
| titleOfInvention |
Cancer specific promoter |
| abstract |
The present invention relates to cancer-specific regulatory sequences that direct expression of a polynucleotide encoding a therapeutic gene product for the treatment of cancer. Specifically, the present invention includes regulatory sequences specific for breast cancer, prostate cancer and pancreatic cancer. The two breast cancer specific sequences utilize specific regions of the topoisomerase IIα and transferrin receptor promoters, particularly in combination with enhancers. Prostate cancer-specific and pancreatic cancer-specific control sequences utilize a composite of tissue-specific control sequences, two-step transcription amplification sequences and post-transcriptional control sequences. In more specific embodiments, these polynucleotides are administered in combination with liposomes. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2010114143-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2017023135-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-5963363-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-5733705-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10738324-B2 |
| priorityDate |
2004-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |