| abstract |
The present invention provides an IL-9 poly- hydride that exhibits stability of antibodies or antibody fragments, undetectable levels of aggregation, and very little or no loss of biological activity, even when stored for long periods of time. A liquid formulation of an antibody or antibody fragment that immunospecifically binds to a peptide is provided. In particular, the present invention is substantially free of amino acids other than surfactants, carbohydrates, sugar alcohols and histidine (preferably having a pKa value of less than 5 and 7 or more), and / or other common excipients, IL -9 liquid preparations of antibodies or antibody fragments that immunospecifically bind to a polypeptide. The present invention further relates to diseases or disorders associated with or characterized by abnormal expression and / or activity of IL-9 polypeptides, and IL-9R or one or more thereof, utilizing the liquid formulations of the present invention. Diseases or disorders associated with or characterized by abnormal expression and / or activity of subunits, autoimmune diseases, inflammatory diseases, proliferative diseases, or infectious diseases (preferably respiratory infections), or Provide a method for the prevention, treatment or amelioration of one or more symptoms. [Selection] Figure 1 |