| abstract |
A compound having the general structure shown in formula (1) or a pharmaceutically acceptable salt and / or solvate thereof is effective for treating diseases or symptoms mediated by the NK1 receptor (eg, vomiting, depression, anxiety, and cough). It is useful for the treatment of various physiological disorders, symptoms or diseases). In a further embodiment, the present invention is, condition or disease treatment NK 1 receptors in a patient in need is involved (i.e., diseases NK 1 receptors are involved in a part of the course of disease or disease NK 1 receptors are involved) Relates to a method for treating |