abstract |
A novel form of N-AChE of acetylcholinesterase (AChE) having a transmembrane domain is provided. Also provided are exons that encode this novel form, peptides that include a transmembrane domain, and antibodies that recognize this novel form. N-AChE expression in the hippocampus correlates with Alzheimer's disease, and its detection using anti-N-AChE antibodies may be a novel diagnostic method for this disease. [Selection figure] None |