abstract |
Disclosed is a new drug that overcomes one or more drawbacks of drugs commonly used in immunosuppression or in the treatment or prevention of inflammatory and autoimmune diseases. A compound represented by the following structural formula: or a pharmaceutically acceptable salt, solvate or inclusion compound containing the compound. The variables of structural formula (I) are as described herein. The present invention meets the aforementioned need by providing some acrylonitrile that inhibits the production of IL-2. These compounds are particularly useful for immunosuppression and / or for treating or preventing inflammatory and immune diseases. [Selection figure] None |