http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2007529485-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-02 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-437 |
| filingDate | 2005-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2007-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2007529485-A |
| titleOfInvention | Pyrazolo '3,4-B! Pyridine compounds and their use as type 4 phosphodiesterase (PDE4) inhibitors |
| abstract | The present invention provides a compound of formula (I) or a salt thereof: Formula (I) wherein W is Ar, -CR 4 R 5 Ar, or a group (y) or (y1) Wherein Ar is (x) or (z): formula (x), (z), (y), (y1); R 1 is C 1-4 alkyl, C 1-3 fluoroalkyl, or- CH 2 CH 2 OH; R 2 is C 2-6 alkyl, C 3-6 cycloalkyl, or — (CH 2 ) n 4 -C 3-6 cycloalkyl; and R 3 is optionally Is optionally substituted C 3-8 cycloalkyl, optionally substituted mono-unsaturated C 5-7 cycloalkenyl, optionally substituted heterocyclic group (aa), (bb) or (cc) (wherein Y is O, S, SO 2 or NR 10 ) or a bicyclic group (ee): Formula (aa), (bb), ( cc), (ee)). The present invention relates to the use of compounds as therapeutics as inhibitors of type IV phosphodiesterase (PDE4) and / or inflammatory and / or allergic such as chronic obstructive pulmonary disease (COPD), asthma, rheumatoid arthritis or allergic rhinitis. It also relates to the use for the treatment and / or prevention of sexually transmitted diseases. [Selection figure] None |
| priorityDate | 2004-03-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 322.