| abstract |
A topical "pour-on" for treating animals suffering from parasites known to be sensitive to salicylanilide, particularly closantel, alone or with at least one avermectin or other antiparasitic compound of the milbemycin type The anti-parasiticidal composition presented as an “agent” product comprises at least 20% (v / v) one or more alcohols, and optionally polyvinylpyrrolidone (PVP), polyoxy Providing a delivery system comprising a polymer component selected from the group consisting of propylene / polyoxyethylene block copolymers (poloxamers) and polyethylene glycols (PEG) provides increased bioavailability of salicylanilide, for example (closantel) As assessed for plasma levels of To improve the bioavailability of closantel. |