Predicate |
Object |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-092 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-195 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P27-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-39 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-00 |
filingDate |
2003-12-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate |
2007-10-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
JP-2007528839-A |
titleOfInvention |
Vaccine containing recombinant pneumococcal ClpP protein |
abstract |
The present invention relates to a vaccine comprising a recombinant ClpP protein of Streptococcus pneumoniae. In the present invention, it was proved that the ClpP moved into the cell wall after heat shock. Immunization of mice with Streptococcus pneumoniae ClpP prior to additional administration of pathogenic D39 is systemic at levels comparable to those obtained when using the well-known pneumococcal protein vaccines PspA and Ply. Induced protective immunity against the disease. Thus, the pneumococcal ClpP of the present invention can be used as an antigen for a vaccine. |
priorityDate |
2003-12-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |