| abstract |
The present invention provides a novel method for inhibiting or reducing steroid-dependent gene activation comprising administering at least two compounds that act at different stages within the gene activation pathway of a steroid receptor and It contains a composition. Preferred methods include administering a first compound capable of inducing degradation of a steroid receptor and administering a second compound capable of inhibiting gene activation at different stages of the steroid receptor pathway. Can be included. Steroid-dependent gene activation can be greatly reduced or inhibited, regulated, or controlled when at least two compounds are administered in combination or together. |