| abstract |
Formula (I): Of the aryl-substituted purine analogs, wherein the variables are as described herein. Such compounds can be used to modulate specific receptor activity in vitro and in vivo and are particularly useful for the treatment of diseases associated with pathological receptor activity in humans, pets and livestock. Also provided are pharmaceutical compositions and methods of treating such diseases using the compounds, as well as methods of using such ligands for receptor localization studies. |