| abstract |
The present invention relates to a novel 2-pyridinyl [7 (pyridin-4-yl) pyrazolo [1,5-a] pyrimidine having at least one substituent on the 4-pyridinyl ring having the formula (I) -3-yl] methanone. Neurological or psychiatric disorders including GABA and / or GABA receptor mediated seizures, neurodegenerative disorders and other movement disorders, neonatal intracerebral hemorrhage and spasticity by modulating GABA and GABA receptor physiology And a composition comprising formula (1) that elicits in a mammalian subject a therapeutic response that alleviates other psychiatric and neurological disorders. [Selection figure] None |