Predicate |
Object |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D493-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-365 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-77 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-93 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D493-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D407-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-343 |
filingDate |
2005-03-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate |
2007-09-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
JP-2007526331-A |
titleOfInvention |
Triptolide lactone ring derivatives as immunomodulators and anticancer agents |
abstract |
Disclosed are compounds based on lactone ring variants of triptolide and hydroxylated triptolide for use in therapies such as anti-proliferative, anti-cancer and immunosuppressive therapies. The present invention relates to compounds useful as immunosuppressive agents, anti-inflammatory agents and anticancer agents. The compounds of the present invention are triptolide derivatives or hydroxylated triptolides resulting from alkylation or acylation of furanoid (lactone) rings as described herein. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2016515530-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20200065056-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-7096559-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2021504455-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-102473019-B1 |
priorityDate |
2004-03-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |