| abstract |
A chemical erosion drug delivery system is provided that allows sustained release of a therapeutic agent within a treatment site for an extended period. A chemical erosion controlled drug delivery system that is inserted into the posterior portion of the eye includes a mixture of a biodegradable polymer (preferably poly (lactide-co-glycolide), PLGA) and a hydrophobic pharmaceutically active agent. . A chemical erosion controlled drug delivery system comprising the following: a mixture of biodegradable polymer and therapeutically effective amount of a hydrophobic pharmaceutically active agent, with increasingly lower concentrations of pharmaceutically active When compared to a comparison system with a drug, (i) has a release rate of a pharmaceutically active drug that is less than, higher than, equal to, or lower than that of the comparison system. And / or (ii) have a release period of the pharmaceutically active agent that is the same as or longer than the comparison system. |