| abstract |
The present invention is directed to general formula (I) Wherein A is selected from one or more X, Y and / or Z groups, X represents a substituted or unsubstituted methylene group, Y represents a substituted or unsubstituted C 2 -alkenylene, or C 2 -alkynylene, Z represents a C 3-7 cycloalkyl group, n represents an integer in the range of 1-7, R 1 represents a substituted or unsubstituted heteroaryl or naphthalenyl type group, R 7 represents a hydrogen atom or a C 1-6 alkyl group, and R 8 represents a hydrogen atom or a C 1-6 alkyl, C 3-7 cycloalkyl, C 3-7 cycloalkyl-C 1-3 alkylene group]. Relates to compounds. The compounds of the invention are in the form of a base, acid addition salt, hydrate or solvate. These compounds have inhibitory activity against the FAAH enzyme. |