| abstract |
In this case, substituted arylthiourea compounds of structural formula I useful as antiviral agents and pharmaceutically acceptable salts of such compounds are presented. Certain substituted arylthioureas disclosed herein are effective and / or selective inhibitors of viral replication, particularly hepatitis C virus replication. In this case, pharmaceutical compositions comprising one or more substituted arylthiourea compounds and one or more pharmaceutically acceptable carriers, excipients or diluents are presented. Such pharmaceutical compositions are those containing a substituted arylthiourea as the only active agent, or a combination of a substituted arylthiourea derivative and one or more other pharmaceutically active agents. This case further presents a method for treating hepatitis C virus infection in mammals. Structural formula I |