| abstract |
Acute, inflammatory and neuropathic pain, toothache, general headache, migraine, cluster headache, mixed vascular and non-vascular syndrome, tension headache, general inflammation, arthritis, rheumatic disease, osteoarthritis, inflammatory bowel Disorders, inflammatory eye disorders, inflammatory or unstable bladder disorders, psoriasis, skin complaints with inflammatory components, chronic inflammatory conditions, inflammatory pain and related hyperalgesia and allodynia, neuropathic pain and related Hyperalgesia and allodynia, diabetic neuropathic pain, causalgia, sympathetic dependence pain, afferent block syndrome, asthma, epithelial tissue damage or dysfunction, herpes simplex, respiratory organs, genitourinary organs, gastrointestinal or vascular organs Movement disorders, wounds, burns, allergic skin reactions, pruritus, vitiligo, general gastrointestinal disorders, gastric ulcers, duodenal ulcers, diarrhea, gastric lesions induced by necrotic substances, Hair growth, vasomotor or allergic rhinitis, for use as vanilloid receptor ligands for the treatment of bronchial disorders or bladder disorders, pyrimidine ethers and compositions containing them (R 1 -R 4 and X, wherein As defined in the section). |