| abstract |
The present invention provides compounds of formula (I) wherein R 6 is C 1 -C 10 alkyl, C 2 -C 10 alkenyl, C 2 -C 10 alkenyl,-(CR 7 R 8 ) t (C 6 -C 14 aryl), and-(CR 7 R 8 ) t (4-10 membered heterocycle) wherein C 6 -C 14 aryl and 4-10 membered heterocycle are optionally halo, C 1 -C 10 Selected from alkyl, —OR 7 , and optionally substituted with at least one substituent selected from —N (R 7 R 8 )], an aqueous solution, an organic solvent, or organic and Treatment with a biocatalyst in an aqueous solvent mixture [wherein at least one stereoisomer is selectively hydrolyzed], in formula (I), wherein R 6 is hydrogen It relates to a process for producing the stereoisomerically enhanced compounds shown. |