| abstract |
The present invention relates to novel 4- (methylsulfonylamino) phenyl analogs as potent vanilloid receptor antagonists and pharmaceutical compositions containing the same. The compounds of the present invention are painful, acute pain, chronic pain, neuropathic pain, postoperative pain, migraine, joint pain, neuropathy, nerve damage, diabetic neuropathy, neurodegeneration, neuropathic Skin disease, stroke, bladder hypersensitivity, irritable bowel syndrome, respiratory diseases such as asthma or chronic obstructive pulmonary disease, inflammation of the skin, eyes, or mucous membranes, fever, stomach-duodenal ulcer, inflammatory bowel disease, inflammatory It is useful as an analgesic for preventing, alleviating or treating pain or inflammatory diseases including diseases and urgent incontinence. |