| abstract |
The present invention provides a method for treating obesity, metabolic disorders, eating disorders (eg, bulimia) and diabetes using antagonists for melanin-concentrating hormone (MCH) as well as for melanin-concentrating hormone (MCH). Novel compounds that are antagonists are disclosed. In other aspects, the invention relates not only to pharmaceutical compositions containing such MCH antagonists, but also to methods of preparing such compounds. The compounds of the invention generally have the structure of formula (I), where the substituents are as defined herein. |