abstract |
Fluid medication is delivered to the renal system through the use of an abdominal aortic flow separation assembly. In one aspect, the tubular member (13) expands through the renal ostium and into the aorta (31) by a radially dilatable internal passageway (18) that isolates the outer (33) or inner flow from the aortic blood flow. The radially expandable member (14) on the tubular member (13) has a larger outer diameter than the tubular member (13) and restrains the outer blood flow (33) from the downstream flow of the branch vessel (32). In the expanded configuration, it is located downstream of the drug delivery port (25) that interfaces with the outer flow. One or more liquid agents, such as papaverine, calcium channel blockers, nifedipine, verapamil, fenoldopam, or dopamine DA 1 agonists, during the perfusion of the downstream portion through the inner flow, the outer flow (33) Delivered bilaterally through the kidneys. The drug is also delivered locally to branch lumens extending from other major lumens in the body. |