| abstract |
A combination comprising an antisense oligonucleotide to a gene encoding a mammalian ribonucleotide reductase R2 protein and one or more immunotherapeutic agents such as cytokines, non-cytokine adjuvants, monoclonal antibodies and cancer vaccines. The combination can further include one or more chemotherapeutic agents. A method of treating cancer in a mammal using this combination is also provided. |