abstract |
The present invention relates to compositions, conjugates, and methods for preventing and / or treating certain conditions and / or diseases comprising a therapeutically effective amount of a GLP-1 agonist and a gastrin compound. Combinations of GLP-1 agonists and gastrin compounds include either GLP-1 agonists or gastrin compounds, including but not limited to diabetes, hypertension, chronic heart failure, fluid retention, obesity, metabolic syndrome and related diseases and disorders Provides a beneficial effect, particularly a sustained beneficial effect, in preventing and / or treating a condition and / or disease that has been proven to have a therapeutic effect thereon. The combination of GLP-1 agonist and gastrin compound can be selected to provide unexpected additive or synergistic effects. |