abstract |
Oral care compositions, including therapeutic rinses, particularly oral rinses, and uses to provide significantly enhanced antimicrobial activity, thereby reducing oral bacteria and promoting overall oral hygiene Is disclosed. The compositions of the present invention are formulated to provide cationic antimicrobial agents with increased bioavailable concentrations, particularly quaternary ammonium compounds such as cetylpyridinium chloride (CPC), and It is useful for the prevention or treatment of oral diseases or symptoms including plaque, caries, gingivitis, periodontal disease and breath odor. The compositions of the present invention can have negative effects on the bioavailability of quaternary ammonium compounds and thus on their antibacterial efficacy, such as anionic, nonionic or amphoteric surfactants. Is found to be essentially free of (found). |