http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2007517870-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-14 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5377 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-501 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-14 |
| filingDate | 2005-01-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2007-07-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2007517870-A |
| titleOfInvention | 6- {4- [4- (1H-indole-2-sulfonyl) -piperazin-1-carbonyl-phenyl]} novel derivative of pyrazidin-3-one |
| abstract | The present invention provides a compound of formula (I) [wherein R 2 is amino, OR 4 group or —Y—R 5 group (wherein R 4 is hydrogen or C 1-4 alkyl, Y is C 1- 4 alkylene, R 5 is hydrogen, halo, hydroxy, C 1-2 alkoxy, C 1-2 alkoxy C 1-2 alkoxy C 1-4 , or an NR 7 R 8 group, wherein R 7 and R 8 Is independently selected from hydrogen, C 1-2 alkyl, hydroxy C 1-2 alkyl or alkoxy C 1-2 alkyl, or R 7 and R 8 together with the nitrogen atom to which they are attached, a heteroatom And n is 1 or 2, and each R 1 is halo, haloC 1-2 alkyl, hydroxy, oxo, amino and C 1-2 alkylamino Heterocyclic derivatives] are independently selected from di -C 1-2 dialkylamino, or a pharmaceutically acceptable salt thereof. These compounds have antithrombotic and anticoagulant properties and are therefore useful in human or animal therapeutic methods. The invention also relates to a method for preparing said heterocyclic derivatives, pharmaceutical compositions containing them, and their use in the manufacture of a medicament for use in the production of antithrombotic or anticoagulant effects. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2015523354-A |
| priorityDate | 2004-01-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 411.