| abstract |
The present invention relates to an antipsychotic or antidepressant (A), an histamine H 3 receptor antagonist and / or inverse agonist (B) in which a harmful effect is weight gain or sedation in a pharmaceutically acceptable vehicle. Wherein the antagonist and / or inverse agonist of the histamine H 3 receptor is associated with a medicament present in an amount to ensure at least one of the following three effects, wherein the three effects are: Suppressing or limiting the adverse effects of increase, at least limiting, awakening, suppressing or limiting adverse effects due to epilepsy / convulsions, increasing the precognitive effects of treatment. The present invention also relates to the preparation of such antagonists or inverse agonists to prepare a medicament that ensures at least one of the three effects in patients treated with, for example, antipsychotic or antidepressants. |