| abstract |
Novel anti-IL-23p40-specific human Ig derived proteins, including without limitation antibodies, fusion proteins and mimetibodies, isolated nucleic acids, vectors, host cells, trans, encoding the anti-IL-23p40 Ig derived proteins The transgenic animals or plants, and methods for making and using them, are useful for therapeutic compositions, methods and devices. Preferably, the anti-IL-23p40 specific human Ig derived protein does not bind the p40 subunit of IL-12 and thus does not neutralize IL-12 related activity. |