abstract |
The present invention relates to a compound of formula (1) wherein the dashed line represents a single or double bond, or no bond is present, and A 1 to A 9 , Q, R 1 to R 11 , T, U , V, W 1 -W 3 , X 1 , X 2 , Y and Z are as defined in the claims and specification), pharmaceutical compositions comprising the compounds, and abnormal cell growth, The use of compounds for the manufacture of a medicament for the treatment of diseases involving unwanted cell proliferation, abnormal mitosis and / or unwanted mitosis. |