| abstract |
The compounds of formula (I) are described herein. This compound can be used, for example, to modulate growth hormone secretagogue receptor (GHS-R). In some examples, the compound can be used to treat obesity. This compound is a spirocyclic compound. The compounds can be used for therapeutic uses including modulation of disorders, diseases or disease symptoms in subjects (eg, mammals, humans, dogs, cats, horses). The compounds include useful GHS-R antagonists. Such antagonists can be used, for example, to reduce food intake in a subject. |