abstract |
The present invention is an inhibitor of dipeptidyl peptidase-IV enzyme ("DP-IV inhibitor"), and is useful for the treatment or prevention of diseases involving dipeptidyl peptidase-IV enzyme such as diabetes, particularly type 2 diabetes. Condensed phenylalanine derivatives are targeted. The present invention is also directed to pharmaceutical compositions comprising these compounds, and the use of these compounds and compositions in the prevention or treatment of diseases involving dipeptidyl peptidase-IV enzymes. |