| abstract |
The present invention relates to β-amyloid production such as neurodegenerative diseases such as Down's syndrome, memory and cognitive impairment, dementia, amyloid neuropathy, encephalitis, nerve and brain injury, vascular amyloidosis, or cerebral hemorrhage with amyloidosis Protein kinases PKCα, PKCβ, PKCγ, PKCε, PKCθ, CDK-1, KDR, PKA, Flt-1, Flt-2 for the treatment and / or prevention of neurological and vascular disorders associated with aggregation Having activity against Flt-3 or Flt-4, or combinations of the above enzymes, Formula I [Chemical 1] Or an pharmaceutically acceptable salt thereof. |