http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2007508830-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12M21-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12M35-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12M25-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12M29-10 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12M3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-07 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12M3-06 |
| filingDate | 2004-10-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2007-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2007508830-A |
| titleOfInvention | Method and bioreactor for culturing and stimulating cell transplants with three-dimensional, biological and mechanical resistance |
| abstract | Method and bioreactor for culturing and stimulating three-dimensional, biological and mechanical resistant cell transplants Three-dimensional, biological and mechanically resistant cell culture capable of culturing and stimulating in a short time or simultaneously There is the challenge of creating methods and bioreactors for manufacturing. This bioreactor allows transplant culture suitable for GMP in conditions where sterility is guaranteed. The bioreactor (1) is intimately and aseptically connected to the reactor closure (21), and at least one of the placement surface for the implant (11) and the miniactuator (14) is implemented. It consists of a basic body that forms two reactor chambers. Furthermore, the bioreactor (1) has at least two hose coupling connections (19) for medium injection and medium discharge or gas injection. The present invention provides a three-dimensional, biological and mechanical resistant cell culture, preferably GMP of chondrocyte structures, that can be cultured and stimulated simultaneously in a closed mini-bioreactor, continuously or at time-controlled intervals. Enable suitable manufacturing. The transplants thus bred are used as tissue replacement material for the treatment of connective and supportive tissue defects, direct joint disorders, rheumatism and degenerative joint diseases, for example, and for knee arthritis the conventional (surgical) treatment method As an example, it can be alternative to microfracturing or perforation. [Selection] Figure 3 |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2016533189-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012118304-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101313769-B1 |
| priorityDate | 2003-10-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 25.