http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2007507482-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-5377 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5377 |
| filingDate | 2004-09-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2007-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2007507482-A |
| titleOfInvention | Salts and polymorphs of pyrrole-substituted indolinone compounds |
| abstract | The present invention relates to 5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indole-3-ylidene) methyl] -N-[(2) -2 shown in Structural Formula 1. -Hydroxy-3-morpholin-4-ylpropyl] -2,4-dimethyl-1H-pyrrole-3-carboxamide non-hygroscopic, eg maleate, and crystalline polymorphs of these salts. The present invention further provides 5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indole-3-ylidene) methyl] -N-[(2S) -2-hydroxy-3 -Morpholin-4-ylpropyl] -2,4-dimethyl-1H-pyrrole-3-carboxamide, and a pharmaceutical composition comprising the salt, and a method for treating diseases such as cancer using the composition. |
| priorityDate | 2003-10-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 400.