http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2007506784-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-473 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4741 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-056 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-473 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4741 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K- http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N43-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-44 |
| filingDate | 2004-09-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2007-03-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2007506784-A |
| titleOfInvention | Cererythrin, its analogs and their use in the treatment of bipolar disorder and other cognitive disorders |
| abstract | The present invention relates to the use of chelerythrine and chelerythrine analogs in pharmaceutical compositions for the treatment of prefrontal cortical cognitive impairment, including bipolar disorder among others. The pharmaceutical composition according to the present invention has the chemical formula (I) or chemical formula (II) (wherein R 1 and R 2 are individually H, C 1 -C 3 alkyl, F, Cl, Br, I, OH, Selected from O (C 1 -C 6 alkyl), O—C (═O) — (C 1 -C 6 ) alkyl, or C (═O) —O— (C 1 -C 6 ) alkyl; R 3 Is H or a C 1 -C 6 alkyl group; R 4 , R 5 , R 6 , R 7 and R 8 are independently H, C 1 -C 6 alkyl, F, Cl, Br, I, OH, - (CH 2) n O (C 1 ~C 6) alkyl, - (CH 2) n O -C (= O) - (C 1 ~C 6) alkyl, or - (CH 2) n C ( = O) -O- (C 1 ~C 6) is selected from alkyl; R 9 and R 10, independently, either a H, or C 1 ~ 6 alkyl, or together - (CH 2) m - to generate a form to 5- to 7-membered ring group; n is 0 to 5; m is 1 to 3; and, A - was optionally combined with a pharmaceutically acceptable carrier, additive or excipient, a pharmaceutically acceptable anion of a pharmaceutical grade salt (it makes an amine group and salts quaternized)) of It includes an effective amount of a compound or stereoisomer, pharmaceutically acceptable salt, solvate or polymorph thereof, depending on the structure. [Chemical 1] |
| priorityDate | 2003-09-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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