http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2007506673-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C67-313 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C67-343 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D231-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D277-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C229-30 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C209-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D231-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-716 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-343 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C229-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-313 |
| filingDate | 2004-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2007-03-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2007506673-A |
| titleOfInvention | Process for preparing alkyl esters of difluoroacetoacetic acid |
| abstract | The present invention relates to a three-step process for the preparation of 4,4-difluoro-acetyl-acetic acid alkyl esters. In the first stage, a reaction of 4-chloro-4,4-difluoro-acetyl-acetic acid alkyl ester with a trialkyl-phosphite of formula (III) P (OR 1 ) 3 is carried out (R 1 in the formula Is C 1 -C 4 alkyl, and these R 1 groups may be the same or different when producing an alkyl-phosphonate of formula (IV). The alkyl-phosphonic acid ester of the above formula (IV) is reacted with the amine of the formula (V) in the second step (wherein R 2 and R 3 are independently of each other hydrogen or C 1 -C 4 alkyl Or when combined to form an enamine of formula (VI) is —CH 2 —CH 2 —O—CH 2 —CH 2 —, wherein R 2 and R 3 are as already mentioned Have). The aforementioned enamine is hydrolyzed in the third stage in the presence of an acid. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2010528071-A |
| priorityDate | 2003-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 32.