http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2007505909-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7056 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-23 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K- http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7056 |
| filingDate | 2004-09-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2007-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2007505909-A |
| titleOfInvention | Synthesis and production of pentostatin and its precursors, analogs and derivatives |
| abstract | Methods and compositions for efficiently preparing and manufacturing pentostatin are provided. Also provided are novel pentostatin precursors, pentostatin analogs and derivatives. In one aspect of the invention, a method is provided for total chemical synthesis of pentostatin via a heterocycle expansion pathway. For example, efficiently obtaining heterocyclic pharmaceutical intermediates for drugs such as pentostatin, such as diazepinone precursors, through ring expansion of the O—C—N functional group in hypoxanthine or 2′-deoxyinosine derivatives Can do. The methods and compositions can also be used to synthesize and prepare heterocyclic compounds other than pentostatin, particularly pharmaceutically important heterocyclic compounds. |
| priorityDate | 2003-09-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 224.