http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2007505616-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-53 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-90 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-70 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-90 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-61 |
| filingDate | 2004-09-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2007-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2007505616-A |
| titleOfInvention | Non-antibiotic resistance selection marker-containing selection system |
| abstract | A selection system that does not contain an antibiotic gene, based on the use of the araD gene as a selectable marker retained in a vector inserted into an araD gene-deficient bacterial strain. The araD gene of E. coli encodes L-ribulose-5-phosphate-4-epimerase. A method for selecting cells transformed with a plasmid containing the araD gene. The system is suitable for the manufacture of therapeutics with non-antibiotic selection markers. The araD gene is not essential for host growth, but manipulation of it affects growth under certain selective conditions. Deletion of araD leads to the accumulation of substances that are toxic to the host but not toxic to humans. The araD gene is relatively small, so it can be constructed with a small plasmid that requires less energy to replicate and leads to increased growth rate and yield. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2008511545-A |
| priorityDate | 2003-09-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 220.