Predicate |
Object |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-7158 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-193 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-1709 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4723 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-521 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-53 |
filingDate |
2004-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate |
2007-03-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
JP-2007505048-A |
titleOfInvention |
Method for determining effectors of innate immunity |
abstract |
Described are methods of identifying polynucleotides or polynucleotide patterns that are modulated by one or more sepsis or inflammation-inducing substances and inhibited by peptides. A method of identifying a polynucleotide expression pattern to inhibit an inflammation or septic response. The method comprises contacting a cell with LPS, LTA, CpG DNA and / or an intact microorganism or microbial component in the presence or absence of a cationic peptide; a polynucleotide associated with the cell in the presence and absence of the peptide Detecting the expression pattern and expressing the inhibition of the inflammation or septic response by the pattern in the presence of the peptide. Also included are compounds and methods identified by the methods of the invention. In another aspect, the present invention provides methods and compounds that enhance innate immunity in a subject. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2019006791-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2014076993-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2017002057-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2013515245-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2020169190-A |
priorityDate |
2003-09-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |