| abstract |
The present disclosure relates to the fields of cellular tumorigenesis and cancer biology. More specifically, the present disclosure relates to tumorigenesis and cancer in estrogen responsive cell types. Examples of cell types include testicular tissue, ovarian tissue, and uterine tissue, mammary gland tissue, brain tissue, skeletal muscle tissue, and lung tissue. The disclosure further includes compositions comprising polypeptides, compositions comprising oligopeptides, compositions comprising peptidomimetics, compositions comprising antibodies, and compositions comprising nucleic acids, and tumor formation in estrogen responsive cell types. Relates to pharmaceutical compositions, diagnostic kits and therapeutic kits useful in the diagnosis or treatment of |