| abstract |
The coating composition containing poly (vinyl acetal-co-vinyl alcohol-co-vinyl acetic acid) and poly (vinyl pyrrolidone-co-vinyl acetic acid) has a first physiological activity to elute at different elution rates in vivo. A medical device can be coated with a first layer containing a substance (eg, rapamycin) and a second layer containing a second bioactive substance (eg, dexamethasone). [Selection figure] None |