http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2007502259-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2601-14 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C255-57 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C233-51 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D333-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C235-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C235-78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C235-78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C235-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-197 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C233-11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D333-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C231-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C233-51 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C255-57 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-275 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-404 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-381 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C253-30 |
| filingDate | 2004-08-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2007-02-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2007502259-A |
| titleOfInvention | Inhibitors of matrix metalloproteinases |
| abstract | Formula (I) wherein R 1 is optionally substituted C 4-12 alkyl, C 2-10 alkyl cycloalkyl, C 2-6 alkyl heterocycloalkyl, C 2-6 alkylaryl, or optionally substituted. 5- or 6-membered aryl or heteroaryl (excluding pyridinyl); Z is a bond, CH 2 , O, S, SO, SO 2 , NR 4 , OCR 4 R 5 , CR 4 R 5 O, or Z, R 1 and Q together form an optionally substituted fused tricyclic group; Q is an optionally substituted 5- or 6-membered aryl or heteroaryl ring; X is COR 3 ; R 2, CONH 2, CO 2 H, CO 2 R 7, SO 2 R 7 or SO 2 NR 8 R 9 (when provided that X is CONH 2, R 2 is not CO 2 R 7); R 3 is , OR 6 or NR 8 R 9 ; R 4 and R 5 are independently of each other H, C 1-6 alkyl, or C 1-4 alkylaryl; R 6 is H, C 1-6 alkyl; R 7 is , C 1-6 alkyl; R 8 Oyo R 9 independently of one another, H or C 1-6 alkyl or,, R 8 and R 9, one together with the nitrogen atom to which they are attached, which is selected from O, S and N Or a 5-membered or 6-membered ring that may contain multiple heteroatoms and physiologically functional derivatives thereof, wherein [3- (acetylamino) -4-cyclohexylphenyl] -butanedioic acid and 3- (acetylamino) -4-cyclohexylphenyl] -butanedioic acid diethyl ether; butanedioic acid [3-methoxy-4- (phenylmethoxy) phenyl]; butanedioic acid [4- (phenylmethoxy) phenyl] and its (Excluding physiologically functional derivatives), methods for their preparation, pharmaceutical formulations containing them, and their use as inhibitors of matrix metalloproteinase enzymes (MMP). |
| priorityDate | 2003-08-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 281.