abstract |
The present invention relates to compounds useful as inhibitors of voltage-gated sodium channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compounds in the treatment of various injuries. These diseases, disorders or conditions include acute pain, chronic pain, neural pain or inflammatory pain, arthritis, migraine, cluster headache, trigeminal neuralgia, herpetic neuralgia, systemic neuralgia, epilepsy or epilepsy, Examples include neurodegenerative disorders, mental disorders (eg, anxiety and depression), myotonia, arrhythmias, movement disorders, neuroendocrine disorders, ataxia, multiple sclerosis, irritable bowel syndrome, and incontinence. |