http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2007501779-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D495-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D495-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-407 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4178 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4196 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-541 |
| filingDate | 2004-08-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2007-02-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2007501779-A |
| titleOfInvention | Heterocyclic amide derivatives having glycogen phosphorylase inhibitory activity |
| abstract | Formula (1) {wherein, for example, Z is CH or nitrogen, and R 4 and R 5 together are -S-C (R 6 ) = C (R 7 )-or -C (R 7) = C (R 6) -S- and and; R 6 and R 7, independently, hydrogen, halo, nitro, cyano, hydroxy, fluoromethyl, difluoromethyl, trifluoromethyl, trifluoromethoxy, carboxy And A is phenylene or heteroarylene; n is 0, 1 or 2; r is 1 or 2; R 1 is halo, cyano or carboxy; Y is , -C (O) R 2, -C (O) OR 2, -C (O) NR 2 R 3, - (1-4C) alkyl [optionally substituted] - (2-4C) alkenyl, - SO 2 NR 2 R 3 and -S (O) R 2 (wherein, c is 0, 1 or 2) is selected from; R 2 and R 3 are independently selected from hydrogen, -O (l-4C) alkyl, -S (l-4C) A compound having alkyl, —N (1-4C) alkyl, heterocyclyl, aryl and (1-4C) alkyl [optionally selected], or a pharmaceutically acceptable salt or prodrug thereof, It has glycogen phosphorylase inhibitory activity and is therefore valuable for the treatment of disease states associated with increased glycogen phosphorylase activity. The preparation of compounds and pharmaceutical compositions containing them is described. |
| priorityDate | 2003-08-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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